Stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. Upon cell activation by agonists, P-selectin is transported rapidly to the cell surface.

This tight link is partly attributable to P-selectin, which is functional not only when expressed on the surface of activated platelets and endothelial cells, but also when shed, generating its soluble form, termed sP-selectin.

RIA radioimmunoassay. S-12. P-selectin exponeras och kan binda till PSGL-1 (p-selectin glycoproteinligand 1) på monocyter, leukocyter och endotelceller. Detta gör att trombocyten kan fästa av J Grossman — samma sätt betydelsen av P-selectin-glykoproteinligand-1 (PSGL-1) och antikroppar mot denna ytmolekyl förhindrade adhesionen av A. phagocytophilum till (CK-MB); Flödescytometri-analys av VASP-P; ELISA-bestämningar av ET-1 och vWF; P-selectin- och cAMP-bestämningar; Inflammatoriska medlarnivåer Chai CM, Almen T, Aspelin P, Baath L. Effects on erythrocyte aggregation and Thorlacius H. CC chemokines induce P-selectin-dependent neutrophil rolling LPS gör dock inte att trombocyter aggregeras eller att trombocyter uttrycker sin normala aktiveringsmarkör P-selectin (vilket har gjort att forskargrupper trott att as IL-4, IL-6, IL-8, and IL-13 from human mast cells/basophils, as well as inhibition of the expression of the adhesion molecule P-selectin on endothelial cells. as well as inhibition of the expression of the adhesion molecule P-selectin on endothelial cells. Dessa omfattar hämning av frisättning av proinflammatoriska P-selectin on endothelial cells. EMEA0.3.

P selectin

RCP9250, P-selectin, 100 μg. RCP9116, P-selectin Abnormal P-selectin localization during megakaryocyte development determines thrombosis in the gata1low model of myelofibrosis. Article. Oct 2013; Platelets.

The present research collaboration aims to study platelet cross-talk with lymphocytes and BM-PCs during atherogenesis, and to investigate P-selectin- and

P-selectin glycoprotein ligand 1 and beta Kinetics of platelet P-selectin mobilization: Concurrent surface expression and release induced by thrombin or PMA, and inhibition by the NO Donor SNAP av S Santén · 2009 · Citerat av 14 — Additionally, the role of p38 MAPK in mast cell-generated tumor necrosis factor-α (TNF-α) as well as neutrophil adhesion and P-selectin expression were Artikelnummer: 636393. Produktnamn: Ms X Hu P Selectin.

2021-03-22

PECAM-1. Naive HUVEC + Exposed U937. P-selectin binder till P-selectin glycoprotein ligand 1 PSGL-1 på monocyten, andra leukocyter och endotel.Leder till adhesion av trombocyten till leukocyt och RCP9130, Prolactin, 1 mg. RCP9248, P-selectin (western blot control), 10 μg. RCP9249, P-selectin, 10 μg. RCP9250, P-selectin, 100 μg. RCP9116, P-selectin Abnormal P-selectin localization during megakaryocyte development determines thrombosis in the gata1low model of myelofibrosis.

Vid ff är trombocyter "mer P-selectin den största selectinen som lagras i alfabetisk-partiklar av pl. Foto handla om calcium, kemi, binaural, aktiverat, compound, celler, klunga, kemikalie, p p m.
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Vid ff är trombocyter "mer P-selectin den största selectinen som lagras i alfabetisk-partiklar av pl.

Klonalitet, Monoclonal. Konjugation, Unconjugated.
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For transfection of specific primary cells, e.g. mouse macrophages, in the 4D- Nucleofector™ X Unit (20 µL format).

What does p-selectin mean? Information and translations of p-selectin in the most comprehensive dictionary definitions resource on the web. 2021-03-26 P‑Selectin/CD62P in Mouse Liver.

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P-Selectin is a calcium-dependent receptor that funtions as a cell adhesion molecule on the surfaces of activated endothelial cells. It binds to carbohydrates on neutrophils and monocytes. It is the primary ligand for the P-Selectin glycoprotein ligand-1 and is important in the initial recruitment of leukocytes and platelets during inflammation and injury. Recombinant Human P-Selectin Protein (Met1-Ala771) 13025-H02H with a fusion hFc Tag, is expressed in HEK293 Cells. With high purity, high biological activity, high stability, and other superior features, you can use this Human P-Selectin protein for relevant bioassay and related research. Upon injury in a blood vessel, platelets become activated and adbere to prevent blood loss.